Anti-CD123 (IL3RA), Clone IL3RA/1531
Interleukin 3 receptor alpha (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GMCSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor ? chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chains (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Source | Mouse |
| Clone | IL3RA/1531 |
| Tissue Type | Lymph Node tissue |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual, 50 tests – NanoVIP® |
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