Anti-GCDFP-15 and TTF-1
Gross Cystic Disease Fluid Protein-15 (GCDFP-15), or prolactin-inducible protein, is a polypeptide involved in the immune and reproductive systems. It inhibits T lymphocyte apoptosis and has fibronectin-specific protease activity. GCDFP 15 is expressed in apocrine, lacrimal, ceruminous, and various salivary glands, and serves as a marker of apocrine differentiation. It is found in cystic breast disease fluid and is a specific marker for breast cancer, as well as other cancers like those of the salivary glands, sweat glands, prostate, and lung.
Thyroid Transcription Factor-1 (TTF-1), a 40 kD protein from the NKx2 homeodomain family, regulates thyroid- and lung specific genes. It is a selective marker for adenocarcinomas of the lung and thyroid and is used to differentiate pulmonary adenocarcinoma from metastatic breast carcinoma and mesothelioma.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | EP95+NX2.1/690 |
| Source | Mouse / Rabbit |
| Tissue Type/Cancer Type | Thyroid / Breast Carcinoma tissues |
| Pack | 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 Tests – Automation – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
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