Anti-Estrogen receptor/ESR1
The Estrogen Receptor (ER), encoded by the ESR1 gene (6q25.1), is a 66 kDa nuclear hormone receptor that acts as a ligand-activated transcription factor. Of its two isoforms, ERα is the primary form used in clinical pathology, widely expressed in reproductive (uterus, ovary, breast, prostate) and non-reproductive tissues (bone, cardiovascular system, brain). Clinically, ERα is a key biomarker in breast carcinoma, routinely assessed by IHC to determine hormone receptor status and guide endocrine therapy. ER positivity indicates favorable response to treatments such as tamoxifen or aromatase inhibitors.
| Intended Use | RUO |
|---|---|
| Clone | ESR1/8407R |
| Localisation | Nucleus |
| Antibody Type | Monoclonal |
| Tissue Type/Cancer Type | Breast Tissue |
| Source | Rabbit |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
Related products
-
Anti-Prostate Specific Antigen (PSA)
Read more -
Anti-Prostate Specific Acid Phosphatase (PSAP)
Read more -
Anti-Carcinoembryonic Antigen (CEA)
Price range: $269.00 through $935.00 Select options This product has multiple variants. The options may be chosen on the product page -
Anti-Kappa Light Chain
Price range: $102.00 through $493.00 Select options This product has multiple variants. The options may be chosen on the product page