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Anti-Carbonic Anhydrase IX

SKU: AMD70_GP Categories: , , Tag:

A broad family of zinc metalloenzymes known as carbonic anhydrases (CAs) catalyzes the reversible hydration of carbon dioxide. cerebrospinal fluid, saliva, gastric acid, respiration, calicification, acid-base balance, and bone resorption are just a few of the biological processes in which they are involved. Their subcellular localization and tissue dispersion exhibit a great deal of variability. The only CA isoenzyme known to be related with tumors is carbonic anhydrase 9 (CA9), a transmembrane protein. All clear-cell renal cell carcinomas express it, while normal kidneys and the majority of other normal tissues do not. It might have a role in the transformation and proliferation of cells. In many solid tumors, carbonic anhydrase 9 is regarded as one of the finest cellular indicators of hypoxic areas.

Intended Use

IVD

Clone

rCA9/9937

Localisation

Cell Membrane & Nucleus

Antibody Type

Monoclonal

Tissue Type/Cancer Type

Kidney Tissue

Source

Mouse

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual