Anti-CD23
CD23 is a 45 kDa glycoprotein that is highly expressed on EBV-transformed B lymphoblasts and found on a subpopulation of freshly isolated peripheral blood and tonsil B cells. The CD23 molecule is the same as the B cell’s low affinity IgE receptor. In certain cases of centroblastic/centrocytic lymphoma and B cell chronic lymphocyctic leukemia, CD23 expression has been seen in the neoplastic cells. Functionally, CD23 plays a role in IgE synthesis as well as B cell development and differentiation. Additionally, a soluble version of CD23 is a strong mitogenic factor. CD23 malfunction is linked to diseases such as chronic lymphocytic leukemia and chronic conjunctivitis.
| Intended Use | IVD |
|---|---|
| Clone | FCER2/8511R |
| Localisation | Cell Membrane |
| Antibody Type | Monoclonal |
| Tissue Type/Cancer Type | Tonsil Tissue |
| Source | Rabbit |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
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