Anti-CD3e
CD3e (CD3ε) is a 20 kDa transmembrane protein and an essential component of the CD3 complex, which is closely associated with the T-cell receptor (TCR) on mature T lymphocytes. It plays a vital role in T-cell development, antigen recognition, and intracellular signaling. CD3ε expression is observed in thymocytes, peripheral T cells, and most T-cell neoplasms. It is absent in B cells, myeloid cells, and non-hematopoietic tissues. This antibody is widely used in identifying T-cell lineage and is particularly important in the diagnosis of T-cell lymphomas and other T-cell–related malignancies
| Intended Use | IVD |
|---|---|
| Clone | C3e/8115R |
| Localisation | Cytoplasm |
| Antibody Type | Monoclonal |
| Tissue Type/Cancer Type | Tonsil tissue |
| Source | Rabbit |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
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