Anti-COX2, Clone COX2/3320R
The enzyme cyclooxygenase (COX), also known as prostaglandin H synthase or prostaglandin endoperoxide synthase, consists of two isoforms, COX-1 and COX-2. Both isoforms are associated with inner membranous compartments and represent key enzymes in the conversion of arachidonic acid to prostaglandin. COX-1 is constitutively expressed in most cell types and is involved in the homeostasis of various physiological functions, while COX-2 is considered to be a mitogen-inducible form, associated with biologic events such as injury, inflammation, and proliferation. COX-2 plays an important role in carcinogenesis of various human cancers, including colorectal cancer and cervical cancer. COX-2 has been studied as a key rate-limiting enzyme for prostanoid biosynthesis.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | COX2/3320R |
| Source | Rabbit |
| Tissue Type/Cancer Type | Colon |
| Pack | 6 mL (RTU), 100 Tests – Automation – i6000, 1 mL(Conc.), 0.5 mL (Conc.), 160 tests – Xmatrx Elite, 50 tests – Xmatrx Elite, 5 slides – Xmatrx, 5 slides – Manual, 50 tests – NanoVIP® |
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