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Anti-GCDFP-15 and TTF-1

SKU: AC606GP Categories: ,

Gross Cystic Disease Fluid Protein-15 (GCDFP-15), or prolactin-inducible protein, is a polypeptide involved in the immune and reproductive systems. It inhibits T lymphocyte apoptosis and has fibronectin-specific protease activity. GCDFP 15 is expressed in apocrine, lacrimal, ceruminous, and various salivary glands, and serves as a marker of apocrine differentiation. It is found in cystic breast disease fluid and is a specific marker for breast cancer, as well as other cancers like those of the salivary glands, sweat glands, prostate, and lung.

Thyroid Transcription Factor-1 (TTF-1), a 40 kD protein from the NKx2 homeodomain family, regulates thyroid- and lung specific genes. It is a selective marker for adenocarcinomas of the lung and thyroid and is used to differentiate pulmonary adenocarcinoma from metastatic breast carcinoma and mesothelioma.

Intended Use

IVD

Antibody Type

Monoclonal

Clone

EP95+NX2.1/690

Source

Mouse / Rabbit

Tissue Type/Cancer Type

Thyroid / Breast Carcinoma tissues

Pack

6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 Tests – Automation – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual