Anti-OCT-3/4 [C-10]
![Anti-OCT-3/4 [C-10]](https://biogenex.seosmo.click/wp-content/uploads/2021/10/OCT3-4_AMB84.jpg)
Oct-3/4 (octamer-binding transcription factor-3 & 4), a member of POU transcription factors, was identified as a DNA-binding protein that activates gene transcription via a cis-element containing an octamer motif. It is expressed in early embryonic cells and germ cells and is central to the gene regulatory network responsible for self-renewal, pluripotency, and lineage commitment in embryonic stem cells and induced pluripotent stem cells. Oct3/4 is not expressed in adult tissues. It is the most widely recognized marker of totipotent embryonic stem cells. OCT3/4antibody is a useful aid for classification of specific subtypes of germ cell tumors including seminoma, embryonal carcinoma and intratubular germ cell neoplasia of unclassified type (IGCNU).
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | C-10 |
| Source | Mouse |
| Tissue Type/Cancer Type | Adrenal Gland |
| Pack | 6 mL (RTU), 100 Tests – Automation – i6000, 1 mL(Conc.), 0.5 mL (Conc.), 160 tests – Xmatrx Elite, 50 tests – Xmatrx Elite, 5 slides – Xmatrx, 5 slides – Manual, 50 tests – NanoVIP® |
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