In our research, we have incorporated the Biogenex/OmicsVeu NanoVip instrument into tissue processing workflows that support various assay types, including immunohistochemistry, immunofluorescence, and imaging mass cytometry. The system has been utilized for both primary staining and preparatory steps prior to several spatial biology methodologies.
Operationally, the NanoVip system provides full automation of several routine tissue handling steps—such as antigen retrieval, staining, washing, and cover slipping—which has contributed to reduced manual processing and improved intra-run consistency. The instrument’s automation features, including automated deparaffinization and rehydration, have also supported workflow consistency and more efficient resource allocation.
A feature that has proven helpful is the thermal stability provided by the Peltier heating elements used for the staining process. This type of heating device, also commonly found in PCR machines, enables rapid and precise temperature changes and is a notable aspect of the NanoVip. This capability has allowed us to employ protocol customization tools to adapt staining conditions for various assay requirements, with consideration for antigen retrieval parameters, signal optimization, and downstream compatibility.
Furthermore, NanoVip’s pipette tip-based reagent dispensing system accommodates reduced reagent volumes, allowing us to conserve precious samples and costly antibodies—especially beneficial during assay development and exploratory research phases.
This description is based on our observed use of the system within a research setting. The information provided here reflects operational experience only and should not be construed as an endorsement by myself, my institution, or the State of Texas.